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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.10 µM MDA-MB-468 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.30 µM MDA-MB-468 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 1.00 µM MDA-MB-468 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 3.00 µM MDA-MB-468 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-468 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 30.00 µM MDA-MB-468 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 100.00 µM MDA-MB-468 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.10 µM MDA-MB-231 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.30 µM MDA-MB-231 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 1.00 µM MDA-MB-231 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 3.00 µM MDA-MB-231 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-231 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 30.00 µM MDA-MB-231 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 100.00 µM MDA-MB-231 Homo sapiens p-STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.10 µM MDA-MB-468 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.30 µM MDA-MB-468 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 1.00 µM MDA-MB-468 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 3.00 µM MDA-MB-468 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-468 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 30.00 µM MDA-MB-468 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 100.00 µM MDA-MB-468 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.10 µM MDA-MB-231 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.30 µM MDA-MB-231 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 1.00 µM MDA-MB-231 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 3.00 µM MDA-MB-231 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-231 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 30.00 µM MDA-MB-231 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 100.00 µM MDA-MB-231 Homo sapiens STAT3
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.10 µM MDA-MB-468 Homo sapiens p-STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.30 µM MDA-MB-468 Homo sapiens p-STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 1.00 µM MDA-MB-468 Homo sapiens p-STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 3.00 µM MDA-MB-468 Homo sapiens p-STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-468 Homo sapiens p-STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 30.00 µM MDA-MB-468 Homo sapiens p-STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 100.00 µM MDA-MB-468 Homo sapiens p-STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.10 µM MDA-MB-468 Homo sapiens STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.30 µM MDA-MB-468 Homo sapiens STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 1.00 µM MDA-MB-468 Homo sapiens STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 3.00 µM MDA-MB-468 Homo sapiens STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-468 Homo sapiens STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 30.00 µM MDA-MB-468 Homo sapiens STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 100.00 µM MDA-MB-468 Homo sapiens STAT1
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.10 µM MDA-MB-468 Homo sapiens p-STAT5
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 0.30 µM MDA-MB-468 Homo sapiens p-STAT5
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 1.00 µM MDA-MB-468 Homo sapiens p-STAT5
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 3.00 µM MDA-MB-468 Homo sapiens p-STAT5
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 10.00 µM MDA-MB-468 Homo sapiens p-STAT5
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 30.00 µM MDA-MB-468 Homo sapiens p-STAT5
Piperlongumine Influence on protein activity (with and without ligand) Luminex assay 100.00 µM MDA-MB-468 Homo sapiens p-STAT5
Piperlongumine Influence on cell apoptosis Luminex assay 30.00 µM patient derived xenograft 4400 Mus musculus SCID/Beige nude mice p-STAT3